Adsorption Characteristics of Reversed-phase Liquid Chromatography with Various Alkyl Bonded Phases.

Characteristics and mechanism of surface diffusion in reversed-phase liquid chromatography using various alkyl ligand bonded silica gels.

Kinetic and thermodynamic parameters concerning surface diffusion were derived in reversed-phase liquid chromatography (RPLC) systems using a series of silica gel packing materials bonded with C1, C4, C8, and C18 alkyl ligands. In this paper, a more detailed study on some characteristics and the mechanism of surface diffusion in the RPLC systems using the different alkyl ligand bonded silica ge...

In Silico Chromatography: Modeling a New Support for Alkyl-Bonded Phases and a Solvent Phase

Chromatography is a tool to measure molecular interactions, and computational chemistry is a tool to explain molecular interactions. Therefore, reversed-phase liquid chromatography of acidic drugs using a pentyland an octyl-bonded silica gels was quantitatively analyzed in silico. A model pentyland an octyl-bonded silica gel and a methanol phases were constructed for docking with acidic drugs. ...

Reversed-phase high-performance liquid chromatography.

Physical origin of peak tailing on C18-bonded silica in reversed-phase liquid chromatography.

Single component isotherm data of caffeine and phenol were acquired on two different stationary phases for RPLC, using a methanol/water solution (25%, v/v, methanol) as the mobile phase. The columns were the non-endcapped Waters Resolve-C18, and the Waters XTerra MS C18. Both columns exhibit similar C18 -chain densities (2.45 and 2.50 micromol/m2) and differ essentially by the nature of the und...

EVALUATION OF THE USE OF ANIONIC/ NONIONIC MIXED MICELLES IN REVERSED PHASE LIQUID CHROMATOGRAPHY OF CHLOROPHENOLS

The use of aqueous mixed micellar system consisting of sodium dodecyl sulfate (SDS) and polyoxyethylene (23) dodecanol (Brij-35) as the mobile phase in reversed-phase liquid chromatography was studied. A group of chlorophenols was used as the test mixture. Adding organic modifier to the system showed that the use of low concentrations of organic additives improves efficiency in SDS/Brij-35 mixe...